Liver Cirrhosis
What is Liver Cirrhosis?
Liver Cirrhosis is the scarring of the liver. The liver carries out many essential functions including metabolism
regulation, protein synthesis, vitamin and iron storage, bile production, as well as removal of toxins from the
body. If the liver doesn’t function properly, it can lead to severe complications and even death.
Cirrhosis occurs when healthy liver cells are replaced by scar tissues. Every time the liver is injured, it tries to
repair itself and if the liver is continually injured, healthy liver cells are then replaced by scar tissue, leading
to development of Cirrhosis.
Causes
Liver Cirrhosis can be caused by different liver diseases and
conditions. The main causes include:
- Chronic alcohol consumption
- Hepatitis B and C infections
Other causes include:
- Autoimmune Hepatitis, which is a liver disease caused by the body’s own immune system
- Frequent exposure to environmental toxins and drugs
- Non-alcoholic fatty liver disease, which is caused by fat accumulation in the liver
- Poorly formed or blocked bile ducts, which cause the bile to build up in the liver
- Primary Biliary Cirrhosis caused by destruction of the bile ducts that carry bile out of
the liver
- Schistosomiasis, which is a parasitic infection common in developing countries
- Wilson’s Disease caused by accumulation of copper in the liver
Symptoms
Liver Cirrhosis patients may not show any symptoms in the early
stages of the disease. However, when the disease progresses and significant liver damage has
occurred, you will experience the following symptoms:
- Black stools
- Changes in personality and confusion in severe cases
- Fatigue and lethargy
- Fluid accumulation in the abdomen (Ascites)
- Itchy skin
- Jaundice (yellow eyes and skin)
- Loss of weight and loss of appetite
- Nausea
- Red spider-looking spots on your chest and back (Spider Angiomas)
- Sleeping difficulties
- Swelling of the legs (Oedema)
- Vomiting blood
Treatment
The liver damage caused by Cirrhosis cannot be reversed. However,
there are treatment options available to prevent or delay the onset of further damage and
complications. The treatment depends on the cause of the Cirrhosis:
- Cirrhosis caused by chronic alcohol abuse is treated by avoiding alcohol consumption
- Cirrhosis caused by Wilson’s Disease can be treated with medications that get rid of the
copper
- Hepatitis-related Cirrhosis is treated with medication, depending on the type of
Hepatitis infection
- Liver transplant may be necessary for end-stage liver disease patients
Complications and Related Diseases
- Brain confusion due to high levels of toxins in the blood and brain
- High blood pressure in the liver (Portal Hypertension)
- Increased risk of Liver Cancer